Testing

Uncovering the full picture

Ayiden, lives with pLGG.
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Comprehensive Genomic testing = Sometimes referred to as genetic testing, and used to identify types of alterations in genes including those in BRAF is the best way to understand your child’s Low-grade = brain tumor Glioma = brain tumor

Your child’s healthcare team may conduct what is known as Genomic testing = Sometimes referred to as genetic testing, and used to identify types of alterations in genes including those in BRAF to identify whether his or her tumor has a BRAF = a gene that, when altered, may be a driver of pLGG growth Alteration = a type of genomic change (mutation or fusion) in the BRAF gene that may contribute to cancer development and what type it is. While many pLGG tumors are likely to have a BRAF = a gene that, when altered, may be a driver of pLGG growth Alteration = a type of genomic change (mutation or fusion) in the BRAF gene that may contribute to cancer development, not all will.

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You may hear Genomic testing = Sometimes referred to as genetic testing, and used to identify types of alterations in genes including those in BRAF referred to as genetic testing from your child’s healthcare team.

What is Genomic testing = Sometimes referred to as genetic testing, and used to identify types of alterations in genes including those in BRAF?

Genomic testing = Sometimes referred to as genetic testing, and used to identify types of alterations in genes including those in BRAF is extremely important to help your child’s healthcare team. Genomic testing = Sometimes referred to as genetic testing, and used to identify types of alterations in genes including those in BRAF looks to identify any gene Alteration = a type of genomic change (mutation or fusion) in the BRAF gene that may contribute to cancer development within the cells of your child’s tumor. This may help your child’s healthcare team understand how the tumor behaves and what treatments may be most appropriate.

Genomic testing = Sometimes referred to as genetic testing, and used to identify types of alterations in genes including those in BRAF is conducted through a Biopsy = Sample of tumor tissue collected for analysis under a microscope and/or comprehensive genomic testing—a procedure where a sample of tumor tissue (either new or previously collected) is taken for further testing. Every child’s pLGG experience is different, so not everyone will be eligible for a Biopsy = Sample of tumor tissue collected for analysis under a microscope and/or comprehensive genomic testing.

Talk to your child’s doctor about early Genomic testing = Sometimes referred to as genetic testing, and used to identify types of alterations in genes including those in BRAF

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Not all Genomic testing = Sometimes referred to as genetic testing, and used to identify types of alterations in genes including those in BRAF options are the same

Healthcare teams use many different types of genomic tests to determine if your child’s pLGG has a BRAF = a gene that, when altered, may be a driver of pLGG growth Alteration = a type of genomic change (mutation or fusion) in the BRAF gene that may contribute to cancer development; however, some may not be able to detect the most common Alteration = a type of genomic change (mutation or fusion) in the BRAF gene that may contribute to cancer development—a BRAF fusion = 1 of the 2 most common types of BRAF alterations in pLGG (ie, KIAA1549-BRAF fusion).

It is important to speak with your child’s healthcare team to determine which tests are the most suitable, as a variety might be appropriate. Each type of genomic test is unique and can help detect different Alteration = a type of genomic change (mutation or fusion) in the BRAF gene that may contribute to cancer development. Testing the tumor early may help better inform your child’s treatment plan.

For explanations of terms used throughout the site, please see the glossary.

Testing the tumor for all BRAF = a gene that, when altered, may be a driver of pLGG growth Alteration = a type of genomic change (mutation or fusion) in the BRAF gene that may contribute to cancer development can help uncover what may be driving your child’s specific pLGG.

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