Testing
Uncovering the full picture
Ayiden, lives with pLGG.
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Comprehensive Genomic testing = test to identify a BRAF alteration and what type it is is the best way to understand your child’s Low-grade = brain tumor Glioma = brain tumor
Your child’s healthcare team may conduct what is known as “Genomic testing = test to identify a BRAF alteration and what type it is” to identify whether his or her tumor has a BRAF = a gene that, when altered, may be a driver of pLGG growth Alteration = a type of genomic change (mutation or fusion) in the BRAF gene that may contribute to cancer development and what type it is. While many pLGG tumors are likely to have a BRAF = a gene that, when altered, may be a driver of pLGG growth Alteration = a type of genomic change (mutation or fusion) in the BRAF gene that may contribute to cancer development, not all will.
You may hear Genomic testing = test to identify a BRAF alteration and what type it is referred to as genetic testing from your child’s healthcare team.
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What is Genomic testing = test to identify a BRAF alteration and what type it is?
Genomic testing = test to identify a BRAF alteration and what type it is is extremely important to help your child’s healthcare team. Genomic testing = test to identify a BRAF alteration and what type it is looks to identify any gene Alteration = a type of genomic change (mutation or fusion) in the BRAF gene that may contribute to cancer development within the cells of your child’s tumor. This may help your child’s healthcare team understand how the tumor behaves and what treatments may be most appropriate.
Genomic testing = test to identify a BRAF alteration and what type it is is conducted through a Biopsy = Sample of tumor tissue collected for analysis under a microscope and/or comprehensive genomic testing—a procedure where a sample of tumor tissue (either new or previously collected) is taken for further testing. Every child’s pLGG experience is different, so not everyone will be eligible for a Biopsy = Sample of tumor tissue collected for analysis under a microscope and/or comprehensive genomic testing.
Talk to your child’s doctor about early Genomic testing = test to identify a BRAF alteration and what type it is
Download the Discussion GuideNot all Genomic testing = test to identify a BRAF alteration and what type it is options are the same
Healthcare teams use many different types of genomic tests to determine if your child’s pLGG has a BRAF = a gene that, when altered, may be a driver of pLGG growth Alteration = a type of genomic change (mutation or fusion) in the BRAF gene that may contribute to cancer development; however, some may not be able to detect the most common Alteration = a type of genomic change (mutation or fusion) in the BRAF gene that may contribute to cancer development—a BRAF fusion = 1 of the 2 most common types of BRAF alterations in pLGG (ie, KIAA1549-BRAF fusion).
It is important to speak with your child’s healthcare team to determine which tests are the most suitable, as a variety might be appropriate. Each type of genomic test is unique and can help detect different Alteration = a type of genomic change (mutation or fusion) in the BRAF gene that may contribute to cancer development. Testing the tumor early may help better inform your child’s treatment plan.
For explanations of terms used throughout the site, please see the glossary.